MDR1 Drugs to Avoid | |
File Size: | 906 kb |
File Type: | mrd1 handouts1.pdf · version 1 |
The Scoop...
If your looking to add an aussie to your family and you haven't come across information pertaining to MDR1, than you haven't done enough research!
MDR1 stands for Multidrug Resistance Mutation. It occurs when there is a mutation on a specific gene. The mutation causes a sensitivity to Ivermectin and many other drugs.
The problem: Your aussie can be negative for MDR1 and still have a reaction to the drugs on the list I provided.
MDR1 stands for Multidrug Resistance Mutation. It occurs when there is a mutation on a specific gene. The mutation causes a sensitivity to Ivermectin and many other drugs.
The problem: Your aussie can be negative for MDR1 and still have a reaction to the drugs on the list I provided.
Play It Safe...
It doesn't matter to me what my dogs MDR1 status is, I treat ALL my dogs and puppies as they are positive (+/+). I constantly repeat myself to my vet, anytime they need a prescription or surgery I remind them. It could mean life or death.
Don't get me wrong tho, if there is no other treatment available and there is a less risky drug than that is what I use with minimal dosing. BUT I keep a constant eye on my dog while they receive their treatment. I am not a vet, nor am I telling you what is best. It is up to you and your vet to decided the best treatment. They see many animals in one day so a friendly reminder before treatment is always a good idea.
Edit- As of 2023 there have been some changes to the chart above that I haven't had the opportunity to fix yet. Your vets should have an updated list or feel free to check for yourselves at https://prime.vetmed.wsu.edu/2022/03/01/problem-medications-for-dogs/
Don't get me wrong tho, if there is no other treatment available and there is a less risky drug than that is what I use with minimal dosing. BUT I keep a constant eye on my dog while they receive their treatment. I am not a vet, nor am I telling you what is best. It is up to you and your vet to decided the best treatment. They see many animals in one day so a friendly reminder before treatment is always a good idea.
Edit- As of 2023 there have been some changes to the chart above that I haven't had the opportunity to fix yet. Your vets should have an updated list or feel free to check for yourselves at https://prime.vetmed.wsu.edu/2022/03/01/problem-medications-for-dogs/
Symptoms To Watch For:
When there has been a buildup of toxins in the brain, your dog will start to show neurological symptoms, such as weakness, lethargy, ataxia, disorientation, tremors, seizures, blindness, and death. When any of these symptoms occur, call your veterinarian immediately. Certain drugs have reversal agents, but others don’t, and only supportive care can be given (IV fluids, nutritional support, and diligent monitoring). Recovery can take a long time due to the nature of the toxins remaining in the brain.
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